BREAKING THE CHAIN
PROMISING ANTI-HIV TREATMENT
NEW HOO-IMM PLUS
FDA - Approved GMP - Certified Patented US-FSM - Registered

A Successive anti-HIV treatment, reduce viral load, increase number of CD4 T-cells,
reduce intact provirus, eventually eliminating HIV infection.

Immuno Modulator

A drug that regulates the immune response. HOO-IMM PLUS helps to restore the balance of the immune system by restoring the CD4 T-cells in HIV patient which is otherwise low due to viral attack. The treatment regulates 10-20 % of overall CD4 T-cells.

No Virologic Failure

ARVs inability to long term suppress the virus results in increase in viral RNA load. "The No Virologic Failure" ability of HOO-IMM PLUS effectively results the patient's viral load at undetectable level; a positive outcome of patient receiving HOO-IMM PLUS over ARVs.

Successive Viral Decay

A process in which a virus gradually losses its ability to replicate and spread over the time. Its an important factor in controlling and eventually eliminating HIV infection. With HOO-IMM PLUS treatment accelerate the rate of viral decay. This has been observed in patient with decline proviral DNA (infected CD4 cells/ cell associated HIV DNA)

Who We Are

about hafl bg

Opening Hours

  • Monday - Friday 10:00 - 21:00
  • Saturday 10.00 - 18.00
  • Sunday Closed

Visitors Hours

  • Monday - Friday 10:00 - 21:00
  • Saturday 10.00 - 18.00
  • Sunday Closed

Hootone Remedies is an Indian pharmaceutical firm registered with FDA and manufacturing according to cGPM Standard Specifications, following the traditional time proven Indigenous Indian ethics of Unani-Ayurvedic system in concurrence with the most modern medical findings, exercising our own innovative techniques for developing drugs for the dreaded diseases like AIDS, Cancer, Leukemia, Hepatitis, Kidney failure, Heart problems & Liver diseases etc confronting the cotemporary world.

Hootone Remedies aims at researching & developing herbal drugs, especially the life saving ones not available in any other system at present and our R&D wing had several landmark achievements to its credit, like formulating the most outstanding anti-retroviral herbal drug HOO-IMM PLUS which recorded 98% inhibition in invitro test.

ANTI-HIV DRUG

about hafl bg






Call Now/Whatsapp

(+91) - 9594000093

Why Patients choose HOO-IMM PLUS?

HOO-IMM PLUS, a plant based dual target HIV drug, works by inhibiting 2 different enzymes that are critical for HIV replication; (IN) Integrase & (RT) Reverse Transcriptase, thus prevent the virus from replicating and spreading throughout the body and reduce the risk of drug resistance that overall improves the treatment outcome.

Invitro IC50 values, measured for HOO-IMM PLUS was the lowest in micro molar concentration against integrase and Reverse transcriptase viral enzymes indicating their potency against the viral enzymes.

Invitro anti-HIV assays, determine the HOO-IMM PLUS activity against 3'processing reaction of integrase enzymes making HOO-IMM PLUS one such kind of 3'processing inhibitor, works by blocking the enzyme called HIV integrase, responsible for the integration of viral DNA into human genome. The 3' processing inhibition leads to the decline in the integrated viral DNA leading to innovative strategic cure therapy.

5 way actions to combat HIV with the New HOO-IMM PLUS:-
1) Successive Viral Decay (Decline in Latent Viral Reservoir - HIV Proviral DNA)
2) No Virological failure (No Viral RNA rebound).
3) Successive CD4 cell recovery (Improves CD4/CD8 ratio).
4) Prevents against Opportunistic Infections (OIs)
5) Productive & Quality Life.

PRECLINICAL & CLINICAL OUTCOME

  • REVERSE TRANSCRIPTASE ASSAY
  • INTEGRASE ASSAY
  • IMMUNO MODULATOR
  • NO VIROLOGIC FAILURE
  • SUCCESSIVE VIRAL DECAY
  • ALLOSTERIC SITE INHIBITOR

INVITRO ANTI-HIV DRUG REVERSE TRANSCRIPTASE ASSAY

The New upgraded HOO-IMM PLUS had undergone the invitro anti-HIV colorimetric test in order to determine the percent inhibition of the drug against the (RT) Reverse Transcriptase that is very important target of HIV.

The kit used for the above test is as under: 1) HIV-1 reverse transcriptase Assay (Xpress Bio, USA)

The IC50 for the New Upgraded HOO-IMM PLUS was recorded at 0.950 µM against the most preferred ARVs (EFA) which is 1.472 µM

INVITRO ANTI-HIV DRUG INTEGRASE ASSAY

The New upgraded HOO-IMM PLUS had undergone the invitro anti-HIV colorimetric test in order to determine the percent inhibition of the drug against the (IN) Integrase that is very important target of HIV.

The kit used for the above test is as under: 1) HIV-1 integrase Assay for Non Catalytic inhibitor (Xpress Bio, USA)

The IC50 of the New Upgraded HOO-IMM PLUS for the Integrase Non Catalytic Assay was recorded at 1.46 µM against the most preffered ARVs (EVG) which had recorded no inhibition at all for the Integrase Non Catalytic Assay

IMMUNO MODULATOR

A drug that regulates the immune response. HOO-IMM PLUS helps to restore the balance of the immune system by restoring the CD4 T-cells in HIV patient which is otherwise low due to viral attack.

The New Upgraded HOO-IMM PLUS treatment regulates 10-20 % of overall CD4 T-cells.

Biomarker Test : CD4 / CD8 count

NO VIROLOGIC FAILURE

ARVs inability to long term suppress the virus results in increase in viral RNA load. "The No Virologic Failure" ability of HOO-IMM PLUS effectively results the patient's viral load at undetectable level; a positive outcome of patient receiving HOO-IMM PLUS over ARVs.

Biomarker Test : HIV RNA Quantitative

SUCCESSIVE VIRAL DECAY

A process in which a virus gradually losses its ability to replicate and spread over the time. Its an important factor in controlling and eventually eliminating HIV infection.

With the New Upgraded HOO-IMM PLUS treatment accelerate the rate of viral decay. This has been observed in patient with decline proviral DNA (infected CD4 cells/ cell associated HIV DNA).

Biomarker Test :HIV-1 Proviral DNA Quantitative & Qualitative Test

ALLOSTERIC SITE INHIBITOR

Invitro anti-HIV assays, determine the HOO-IMM PLUS activity against 3'processing reaction of integrase enzymes making HOO-IMM PLUS one such kind of 3'processing inhibitor, works by blocking the enzyme called HIV integrase, responsible for the integration of viral DNA into human genome. The 3' processing inhibition leads to the decline in the integrated viral DNA leading to innovative strategic cure therapy.

Invitro Clinically Tested : The 3' processing inhibition of the New Upgraded HOO-IMM PLUS was measured and evaluated through the Integrase Non Catalytic Assay with Xpress Bio, USA

about hafl bg

MAKE AN APPOINTMENT

If you wont to make an appointment with any specialist just fill up the form with valid data and we will contact you via phone for confirmation.




Brochures


















Our Awards and Achievements

Before After result

teeth before teeth after

WHAT DOCTORS AND MEDICAL EXPERT SAY

25

Years of experience

12537

Happy Patients

15

Number of Doctors

150

Number of Associates

PATIENT TESTIMONIALS

Frequently Asked Questions

Does HIV cure possible?

HIV Cure only Possible - Making visible & inhibiting the latent viral reservoirs ie. HIV proviral DNA
3 Major steps towards HIV Cure:-
1) Reasons why HIV has been such a difficult medical challenge.
2) Any HIV cure requires finding viral reservoirs, "waking" them up, and making them visible for treatment.
3) Making visible & inhibiting the latent viral reservoirs - HIV proviral DNA.

When a person can be called cured from HIV?

The patient records Not Detected for the foremost HIV test which is HIV Proviral DNA PCR Qualitative test, after completing the course of the New HOO-IMM PLUS treatment. The minimum period required for the patient in order to completely eliminate the HIV latent viral reservoir from the body so as to record Negative for HIV Proviral DNA PCR Antigen Test is 12 - 15 months because the treatment targets the HIV latent viral reservoir which is the integrated genetic material of the virus. HIV (Human immunodeficiency virus) a retrovirus is always in the state of a provirus. When a retrovirus invades a cell, the RNA of the retrovirus is reverse-transcribed into DNA by reverse transcriptase, then inserted into the host genome by an integrase. Integration can result in a latent infection or a productive infection. In a productive infection, the provirus is transcribed into messenger RNA which directly produces new virus, which in turn will infect other cells. A latent infection results when the provirus is transcriptionally silent rather than active.
Pro-viral HIV DNA PCR Antigen Test is the foremost confirmatory test to identify the presence of HIV virus in the human body. It’s very sensitive which detects a single copy of HIV gag target DNA at near-theoretical frequency, typically with microgram yields of specific amplification product. All the major infection like TB, Swine Flu, and Hepatitis are confirmed only through DNA PCR Antigen Test. The Proviral HIV DNA PCR will never be recorded Not Detected unless there is not a single HIV viral antigen in the body and once recorded Negative that means the blood sample is absent for the presence of HIV. And once you are negative for the presence of HIV then you are a normal healthy person and will live a normal, healthy and productive life. Once the patient records Negative for HIV Proviral DNA PCR Test then he will completely stop all the medication including HOO-IMM PLUS as well as ARVs.

Can I take HOO-IMM PLUS along with my present ARVs?

The New Upgraded HOO-IMM PLUS course is well suitable for the following patients: 1) Patient those are not under ARVs. 2) Patient those are already undergoing ARVs.
The New upgraded HOO-IMM PLUS medication will also help the patient with ARVs to increase their CD4 count and decrease in HIV RNA viral load count and most importantly the Latent HIV Viral Reservoir (HIV DNA Proviral load count) which is not at all targeted by the ARVs. If the patient has not started ART, then the patient does not required to start ARVS and only start HOO-IMM PLUS. The patient already undergoing ARVs can start the New HOO-IMM PLUS and continue taking ARVS maintaining a gap of 2 hour.

How long is the course of the treatment ?

The minimum period required for the patient in order to completely eliminate the HIV latent viral reservoir from the body so as to record Negative for HIV Proviral DNA PCR Antigen Test is 12 - 15 months because the treatment targets the HIV latent viral reservoir which is the integrated genetic material of the virus.

What are the tests to be undergone while on treatment?

Biomarker or Test Protocol Involved in the Anti-HIV Treatment with HOOIMM PLUS: 1. HIV RNA Quantification Viral load count. 2. CD4 / CD8 count 3. HIV Proviral DNA Quantitative & Qualitative Test

Note: Quantification of HIV reflects the viral load which plays a critical role in determining the phase of infection, deciding the treatment and determining the response to anti-viral treatment.

Online live support

Your health conditions will be regularly monitored by our expert consulting doctors. For online doctor’s consultation for all your queries
email us on info@hootone.org.
You can call us on our Helpline No. +91 9594000093 to talk to our doctor and experts directly.
You can also whatsapp to us your query on +919594000093.

LATEST NEWS

.
.

Get In Touch

Address

Bandra, Mumbai, India

Phone

+91 9594000093

Email

info@hootone.org